CAPTIVA is a two-stage Phase III, double-blind randomized trial to determine if rivaroxaban or ticagrelor or both are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death. 

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CAPTIVA-MRI is an observational multimodal MR imaging study that is sub-study to the CAPTIVA trial .The primary goal of this sub-study is to determine if MRI biomarkers can potentially identify ICAS patients who fail best medical management. 

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ASPIRE is a randomized, double-blinded, phase III study designed to test the efficacy and safety of anticoagulation, compared with aspirin, in patients with a recent ICH and non-valvular AF. 

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The primary goals of SleepSMART trial is to determine whether treatment of obstructive sleep apnea (OSA) with positive airway pressure starting shortly after acute ischemic stroke or high risk TIA reduces recurrent stroke, acute coronary syndrome, and all-cause mortality after the event.

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SATURN is a prospective, randomized, open‐label, and blinded end‐point assessment designed to evaluate the effects of continuation vs. discontinuation of statins on the risk of symptomatic intracerebral hemorrhage recurrence. 

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